Thermo Fisher Scientific GluR2 Polyclonal Antibody
GluR2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 ELISA에 적합합니다. 인간 GluR2(aa 25–230) 재조합 단백질을 면역원으로 사용하였으며, 신경세포 내 흥분성 신경전달 연구에 활용됩니다. 고순도 Affinity Chromatography 정제 및 안정적 PBS/glycerol 저장 조건 제공.
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Thermo Fisher Scientific GluR2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 25–230 of human GluR2/GRIA2 (NP_0010770881) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804088 |
Product Specific Information
Immunogen sequence:
NSIQIGGLFP RGADQEYSAF RVGMVQFSTS EFRLTPHIDN LEVANSFAVT NAFCSQFSRG VYAIFGFYDK KSVNTITSFC GTLHVSFITP SFPTDGTHPF VIQMRPDLKG ALLSLIEYYQ WDKFAYLYDS DRGLSTLQAV LDSAAEKKWQ VTAINVGNIN NDKKDEMYRS LFQDLELKKE RRVILDCERD KVNDIVDQVI TIGKHV
Positive Samples: SH-SY5Y, HL-60, Mouse liver, Mouse brain, Mouse pancreas, Rat brain
Cellular Location: Cell junction, Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Target Information
The ion channels activated by glutamate are divided into two classes:
- NMDA receptors (NMDAR) sensitive to N-methyl-D-aspartate
- AMPA receptors (AMPAR) activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid
AMPARs consist of four Glutamate Receptor Subunits (GluR1–4) and are essential for excitatory neurotransmission in the brain. The GluR2 subunit plays a key role in synaptic plasticity such as long-term depression (LTD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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