Thermo Fisher Scientific SPTBN1 Polyclonal Antibody
Rabbit polyclonal antibody against human SPTBN1. Validated for IHC and IHC-P at 1:100–1:500 dilution. Antigen affinity purified, supplied in liquid form with 0.25 mg/mL concentration. Recommended storage at 4°C, for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 2150 and 2200 of Human Spectrin Non-Erythroid Beta 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Spectrin (Sp), the most abundant erythrocyte membrane skeleton protein, maintains the biconcave shape of red blood cells while providing flexibility and elasticity. Erythrocyte spectrin is a heterodimer of a 280 kDa alpha subunit and a 246 kDa beta subunit, forming a 100 nm rod-like structure. In non-erythroid tissues, spectrin (also known as fodrin) consists of homologous alpha and beta subunits. The nomenclature designates erythrocyte subunits as alpha-1 and beta-1, and fodrin subunits as alpha-2 and beta-2, with alternatively spliced forms (e.g., beta-1 epsilon-1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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