Thermo Fisher Scientific SARS-CoV Spike Protein (SDelta3) Monoclonal Antibody (7G12)
SARS-CoV SDelta3 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IP에 사용 가능. SARS-CoV-2 Spike 단백질과 교차 반응 가능성이 있음. Protein G로 정제된 액상 형태이며, 연구용으로만 사용.
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Thermo Fisher Scientific SARS-CoV Spike Protein (SDelta3) Monoclonal Antibody (7G12)
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7G12 |
| Immunogen | SARS-CoV SDelta3 (within S1 domain) protein (168–461 a.a.) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866557 |
Product Specific Information
May cross-react with SARS-CoV-2 Spike protein.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus that causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The SARS-CoV-2 Spike Protein consists of S1 and S2 domains and serves as the main surface antigen of the coronavirus. The glycosylated Spike protein and nucleocapsid protein can be detected in infected cell culture supernatants using antisera from SARS patients.
The S1 domain contains a receptor-binding domain (RBD) that specifically binds to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
Coronavirus diversity is reflected in the variability of Spike proteins (S proteins), which have evolved to differ in receptor interactions and responses to environmental triggers of virus-cell membrane fusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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