Thermo Fisher Scientific Human IA-1 Synthetic Peptide
인간 IA-1 단백질의 N-말단 19개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20823의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며 PBS(pH 7.2, 0.1% BSA) 완충액에 보관. 연구용으로만 사용 가능.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the amino terminus of human IA-1.
PEP-0937 can be used as a blocking peptide with polyclonal antibody PA5-20823.
Target Information
IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that, while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid-, and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor and is part of several signaling pathways including Notch and Sonic Hedgehog, in addition to Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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