Thermo Fisher Scientific Human IA-1 Synthetic Peptide
인간 IA-1 단백질의 N-말단 19개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20823의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며 PBS(pH 7.2, 0.1% BSA) 완충액에 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP0937
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human IA-1 Synthetic Peptide
Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the amino terminus of human IA-1.
PEP-0937 can be used as a blocking peptide with polyclonal antibody PA5-20823.
Target Information
IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that, while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid-, and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor and is part of several signaling pathways including Notch and Sonic Hedgehog, in addition to Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.