Thermo Fisher Scientific RPRD1B Monoclonal Antibody (OTI1C7), TrueMAB
RPRD1B 단백질을 인식하는 Mouse monoclonal antibody. Western blot과 IHC(Paraffin)에서 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. Affinity chromatography로 정제되어 높은 순도 보장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C7 |
| Immunogen | Full length human recombinant protein of human RPRD1B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
RPRD1B interacts with the phosphorylated C-terminal heptapeptide repeat domain (CTD) of RNA polymerase II subunit POLR2A and participates in CTD dephosphorylation by RPAP2.
Acts as a transcriptional regulator enhancing expression of CCND1 and other cell cycle-related genes (CDK2, CDK4, CDK6, cyclin-E).
Promotes RNA polymerase II binding to promoter and termination regions, facilitating proper transcription termination and chromatin loop formation.
Promotes cell proliferation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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