Thermo Fisher Scientific WDR48 Polyclonal Antibody
Rabbit polyclonal antibody targeting human WDR48 protein. Validated for WB and IHC applications. Supplied as liquid form at 0.1 mg/mL concentration. Provides high sequence identity with mouse and rat orthologs. Suitable for research use only.
- 카탈로그번호
- PA563508
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human WDR48 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649585 |
Product Specific Information
Immunogen sequence:
SDMLQVRKVM EHVYEKIINL DNESQTTSSS NNEKPGEQEK EEDIAVLAEE KIELLCQDQV LDPNMDLRTV KHFIWKSGGD LTLHYR
Antigen sequence identity:
- Mouse: 99%
- Rat: 99%
Target Information
WD-repeats are motifs found in various proteins, characterized by a conserved core of 40–60 amino acids forming a propeller-like structure. Proteins containing WD-repeats participate in diverse cellular functions such as signal transduction, apoptosis, transcriptional regulation, and cell cycle control. These repeats mediate protein-protein interactions and facilitate complex assembly.
WDR48 (WD repeat-containing protein 48), also known as USP1-associated factor 1 or p80, is a 677-amino-acid protein that regulates deubiquitinating complexes via activation of USP1, USP12, and USP46. It enhances deubiquitination by increasing catalytic turnover without altering substrate affinity. WDR48 is ubiquitously expressed and mainly localized to the cytoplasm. Five isoforms are expressed due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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