Thermo Fisher Scientific IL-37 Polyclonal Antibody
Human IL-37 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 PBS 버퍼에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IL-37. Recombinant protein control fragment (Product #RP-96069) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642701 |
Product Specific Information
Immunogen sequence:
ENSGVKMGSE DWEKDEPQCC LEDPAVSPLE PGPSLPAMNF VHTSPKVKNL NPKKFSIHDQ DHKVLVLDSG NLIAVPDKNY IRPEIFFALA
Antigen sequence identity:
Mouse – 24%
Rat – 24%
Target Information
The protein encoded by this gene is a member of the interleukin 1 cytokine family.
This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp).
It also binds to interleukin 18 binding protein (IL18BP), forming a complex with IL18 receptor beta subunit, thereby inhibiting IL18 activity.
This gene, along with eight other interleukin 1 family genes, forms a cytokine gene cluster on chromosome 2.
Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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