Thermo Fisher Scientific IL23R Monoclonal Antibody (OTI5H9), TrueMAB
인간 IL23R 단백질을 인식하는 Mouse monoclonal 항체로 Western blot에 적합합니다. E. coli에서 발현된 IL23R(aa 57-355) 재조합 단백질로부터 유래하였으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. PBS, 1% BSA, 50% glycerol에 보관하며 -20°C에서 보존 가능합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 57–355 of human IL23R produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IL-23R is a 629 amino acid subunit of the receptor for cytokine IL23A/IL23, which pairs with IL12RB1 (IL12Rβ1) to participate in IL23A signaling. This receptor associates constitutively with Janus kinase 2 (JAK2) and binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing produces six isoforms of IL-23R. IL-23R is implicated in psoriasis pathogenesis and is a potential therapeutic target in inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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