Thermo Fisher Scientific TNFRSF10A Monoclonal Antibody (OTI8A12), TrueMAB
인간 TNFRSF10A 단백질을 인식하는 단클론 항체로 Western blot에 적합합니다. OTI8A12 클론이며, 액상 형태로 1 mg/mL 농도입니다. PBS, BSA, 글리세롤로 안정화되어 있으며 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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- TA807496
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Applications
- Western Blot (WB): 1:200–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 263–468 of human TNFRSF10A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also known as TRAIL receptor 1. The ligand for this DR4 death receptor, TRAIL, belongs to the TNF family. DR4, like other receptors such as Fas and TNFR1, mediates apoptosis and NF-κB activation in various cells and tissues. Apoptosis, or programmed cell death, is a key process in normal cellular differentiation and development of multicellular organisms. It is induced by interactions between cytokines of the TNF family (e.g., TNF, Fas ligand) and their death domain-containing receptors (e.g., TNFR1, Fas receptor).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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