Thermo Fisher Scientific HSF2 Monoclonal Antibody (OTI5C1), TrueMAB
Human HSF2 단백질(aa 74-324)을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화됨. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol buffer 포함. 세포 스트레스 반응 연구용, 진단용 사용 불가.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 74–324 of human HSF2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Prokaryotic and eukaryotic cells respond to thermal and chemical stress by inducing heat shock genes. In eukaryotes, this regulation occurs primarily at the transcription level via heat shock transcription factors (HSF1 and HSF2).
HSF1 and HSF2 are upregulated by estrogen at both mRNA and protein levels. HSF1 exists as a monomer under normal conditions and becomes active upon trimerization and nuclear translocation. HSF2 is associated with differentiation and development, and also binds DNA as a trimer. Both are induced by proteasome inhibitors of the ubiquitin pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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