Thermo Fisher Scientific KLF3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human KLF3. Validated for WB and ICC/IF applications. Affinity-purified with >95% purity. Supplied in PBS with glycerol and sodium azide. For research use only.
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- PA577163
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human KLF3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720890 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Krueppel-like factors (KLFs) are a family of evolutionarily conserved zinc finger-containing transcription factors involved in cell growth, proliferation, differentiation, and embryogenesis. Members of the Sp1-like/KLF family can act as activators or repressors depending on promoter binding and interacting coregulators.
KLF6 (also known as Zf9 or CPBP) and KLF3 are Kruppel-like zinc finger transcription factors. KLF6 is induced during hepatic stellate cell activation and can transactivate collagen I promoter-driven reporter genes, suggesting a role in tissue injury response. KLF3 may play a role in hematopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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