Thermo Fisher Scientific IL12RB1 Polyclonal Antibody
IL12RB1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합. Human 및 Rat 시료 반응성 확인. Affinity chromatography로 정제되어 높은 특이성과 재현성 제공. 연구용으로만 사용 가능.
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- PA5104355
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IL12RB1 (Accession P42701), corresponding to amino acid residues C196–E246 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853665 |
Product Specific Information
Antibody detects endogenous levels of total IL12RB1.
Target Information
The protein encoded by this gene is a type I transmembrane protein belonging to the hemopoietin receptor superfamily. It binds to interleukin 12 with low affinity and is a component of the IL12 receptor complex. This protein forms a disulfide-linked oligomer required for IL12 binding activity. Coexpression with IL12RB2 leads to high-affinity IL12 binding and IL12-dependent signaling. Deficiency of this gene is associated with immunodeficiency involving severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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