Thermo Fisher Scientific GPR77 Polyclonal Antibody
Thermo Fisher Scientific의 GPR77 폴리클로날 항체는 인간 C5AR2 단백질을 인식하며 WB, IHC, ICC/IF 실험에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관, 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human C5AR2 (Accession Q9P296), corresponding to amino acid residues A297–V337 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853667 |
Product Specific Information
Antibody detects endogenous levels of total C5ARL.
Target Information
C5AR2 is an orphan member of the anaphylatoxin receptor family. It is a seven-transmembrane G-protein-coupled receptor with an N-terminal N-glycosylation site, conserved cysteines, and potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg, functioning as a regulated scavenger receptor that negatively modulates C5aR-mediated inflammation. Northern blot analysis shows co-expression with C5aR in various tissues and cells, including neutrophils, macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary, and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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