Thermo Fisher Scientific RASGAP Polyclonal Antibody
RASGAP 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot에 1:500~1:2000 희석으로 사용 가능하며, RASA2 단백질의 내인성 발현을 검출합니다. 친화 크로마토그래피로 정제된 액상 항체로, PBS 및 글리세롤 완충액에 보관됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RASA2 (Accession Q15283), corresponding to amino acid residues I811–S850 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853666 |
Product Specific Information
Antibody detects endogenous levels of total RASA2.
Target Information
TACC1 is located on the 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members (TACC1, TACC2, and TACC3) map closely to the corresponding FGFR1, FGFR2, and FGFR3 genes on chromosomes 4, 8, and 10. Since they are phylogenetically related, TACC and FGFR are proposed to have similar roles in cell growth and differentiation. TACC1 contains a conserved C-terminal region as in the Drosophila homolog D-TACC, which is necessary for normal spindle function. Mammalian TACC proteins appear to interact with centrosomes and microtubules in a similar manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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