Thermo Fisher Scientific ESRP2 Polyclonal Antibody
ESRP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human 및 Mouse 시료에 반응. WB와 ICC/IF에 적합하며, 고순도 Affinity chromatography로 정제됨. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5114776
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ESRP2 (Accession Q9H6T0), corresponding to amino acid residues P19–T69 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899412 |
Product Specific Information
Antibody detects endogenous levels of total RBM35B.
Target Information
RBM35A, also known as ESRP2, is an mRNA splicing factor that, together with its related protein RBM35A (ESRP1), coordinates an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A regulate posttranscriptional expression of genes such as FGFR2, CD44, CTNND1, and ENAH by affecting protein translation via the 5′ UTRs of mRNAs. These proteins act as global regulators of epithelial regulatory networks. Loss of this ESRP-regulated splicing program induces epithelial-mesenchymal transition-associated morphological changes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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