Thermo Fisher Scientific AKR1C3 Polyclonal Antibody
AKR1C3 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, IP 등 다양한 응용에 적합. 고순도(>95%) 항원 친화 크로마토그래피 정제. 인간 및 마우스 반응성. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human AKR1C3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719798 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity is >95% (by SDS-PAGE).
Target Information
AKR1C3 is a member of the aldo/keto reductase superfamily, which includes over 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors.
AKR1C3 catalyzes the reduction of prostaglandin (PG) D2, PGH2, and phenanthrenequinone (PQ), and the oxidation of 9-alpha,11-beta-PGF2 to PGD2.
It may play a role in allergic diseases such as asthma and in regulating cell growth or differentiation.
This gene shares high sequence identity with three other gene members and is clustered with them at chromosome 10p15-p14.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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