Thermo Fisher Scientific Zyxin Polyclonal Antibody
Zyxin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도(>95%) 항원 친화 크로마토그래피 정제. 인간, 마우스, 랫트 반응성. 연구용으로만 사용.
- 카탈로그번호
- PA576069
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human Zyxin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719797 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Zyxin is involved in focal adhesions, actin-rich structures that enable cells to adhere to the extracellular matrix and serve as sites for signal transduction complexes. It is a zinc-binding phosphoprotein concentrated at focal adhesions and along the actin cytoskeleton. Zyxin features an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain interacts with SH3-containing proteins, while LIM domains mediate protein-protein binding. Zyxin may act as a messenger in adhesion-stimulated signal transduction and modulate actin bundle organization. Alternative splicing generates multiple transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-76069_Zyxin_Q15942-1_Rabbit.svg, PA5-76069_Zyxin_Q15942-1_Rabbit_PDP.jpeg)
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