Thermo Fisher Scientific UCP3 Polyclonal Antibody
UCP3 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, Western blot에 적합합니다. 인간 및 생쥐 시료 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 장기 보관 시 -20°C 보관을 권장합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human UCP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS (pH 7.2) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2719792 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, uncoupling oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism.
UCP2 is a structurally related protein that also uncouples mitochondrial respiration and is more widely expressed in human and mouse tissues, including white adipose tissue and muscle. UCP2 is thought to play a role in body weight regulation.
An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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