Thermo Fisher Scientific MYOD1 Polyclonal Antibody
Rabbit polyclonal antibody against human MYOD1, suitable for WB and ICC/IF. Detects endogenous MyoD1. Affinity purified, supplied in PBS with glycerol. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MYOD1 (Accession P15172), corresponding to amino acid residues A90–P140 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852270 |
Product Specific Information
Antibody detects endogenous levels of total MyoD1.
Target Information
The Myogenic determination gene (MyoD) was first identified by its ability to convert embryonic mouse fibroblast cells to muscle cells. Forced expression of MyoD (human homolog myf3) can convert various normal and neoplastic cells into muscle cells or activate muscle-specific genes. The regulatory domain of MyoD includes a 70-amino-acid region containing a basic DNA-binding motif and a helix-loop-helix (HLH) dimerization motif. Other genes with similar HLH domains include myf5, myogenin (myf4), and myf6 (MRF4, herculin).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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