Thermo Fisher Scientific ABCG1 Polyclonal Antibody
인간 ABCG1 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 고순도 Affinity Chromatography로 정제됨. 액상 형태로 -20°C 보관, 연구용으로만 사용 가능.
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- PA5102882
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- pk
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Thermo Fisher Scientific ABCG1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ABCG1 (Accession P45844), corresponding to amino acid residues E191–D241 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852265 |
Product Specific Information
Antibody detects endogenous levels of total ABCG1.
Target Information
ATP-binding cassette (ABC) transporter genes are involved in the regulation of dietary cholesterol retention.
ABCG1 (also known as ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages.
It is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein.
Conversely, lipid efflux mediated by HDL(3) suppresses ABCG1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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