Thermo Fisher Scientific SQSTM1 Monoclonal Antibody (6C5)
인간 SQSTM1 단백질을 인식하는 마우스 단클론 항체로, Western blot에 적합. NF-κB 신호전달 경로 연구에 활용 가능. 고순도 Protein G 정제 및 안정적 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SQSTM1 Monoclonal Antibody (6C5)
Applications
- Western Blot (WB)
Tested Dilution
- 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C5 |
| Immunogen | This SQSTM1 antibody is generated from mice immunized with a recombinant protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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