Thermo Fisher Scientific SOD2 Monoclonal Antibody (6C11)

Applications and Tested Dilutions

Product Specifications

Target Information

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O₂⁻) to hydrogen peroxide, which is then converted to O₂ and H₂O by glutathione peroxidase and catalase.
There are several classes of SOD:

• SOD1 (Cu,Zn-SOD): Intracellular, homodimeric enzyme found in all eukaryotes.
• SOD2 (Mn-SOD): Mitochondrial enzyme located in the matrix, containing manganese as a cofactor.
• SOD3 (EC-SOD): Extracellular, heparin-binding multimer expressed in lungs, vessel walls, and airways.
• SOD4 (CCS): Copper chaperone that delivers Cu to SOD1, activating it through cofactor insertion.

Usage Notice

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.