Thermo Fisher Scientific DNAJC13 Polyclonal Antibody
Human DNAJC13 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼와 글리세롤을 포함한 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DNAJC13. Recombinant protein control fragment (Product #RP-96342) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640694 |
Product Specific Information
Immunogen sequence:
VTPGGFDQIN PATNRVLCSY DYRNIEGFVD LSDYQGGFCI LYGGFSRLHL FASEQREEII KSAIDHAGNY IGISLRIRKE PLEFEQYLNL RF
Sequence Identity:
- Mouse: 97%
- Rat: 92%
Target Information
DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans. It is thought to be a co-chaperone of Hsc70, regulating protein conformation at membrane sites and playing a role in intracellular trafficking. It co-localizes with markers of the endosomal system and is involved in membrane trafficking through early endosomes but not degradative organelles. DNAJC13 also regulates the intracellular trafficking of the epidermal growth factor receptor.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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