Thermo Fisher Scientific DNAJC13 Polyclonal Antibody
Human DNAJC13 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 세포 내 막 수송 및 단백질 구성 연구에 적합.
- 카탈로그번호
- PA557873
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DNAJC13. Recombinant protein control fragment (Product # RP-102754) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640695 |
Product Specific Information
Immunogen sequence:
QVRAQTAELF AKMTADKLIG PKVRITLMKF LPSVFMDAMR DNPEAAVHIF EGTHENPELI WNDNSRDKVS TTVREMM
Sequence identity:
- Mouse: 97%
- Rat: 97%
Target Information
DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is a human homolog of a DnaJ domain-containing protein identified in C. elegans endocytic defect screens. It functions as a co-chaperone of Hsc70, regulating protein conformation at membrane sites and participating in intracellular trafficking. DNAJC13 co-localizes with endosomal markers and is implicated in membrane trafficking through early endosomes but not degradative organelles. It also regulates intracellular trafficking of the epidermal growth factor receptor (EGFR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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