Thermo Fisher Scientific Human LGI2 Synthetic Peptide
인간 LGI2 서열의 11개 아미노산으로 구성된 합성 펩타이드. 항체 PA5-20492의 차단 펩타이드로 사용 가능. PBS(pH 7.2), 0.1% BSA, 0.02% sodium azide 함유. -20°C에서 보관. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 11 amino acids near the amino terminus of human LGI2.
PEP-0612 can be used as a blocking peptide with polyclonal antibody PA5-20492.
Target Information
The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar.
The LGI family consists of four highly related proteins containing leucine-rich repeats (LRRs), similar to other transmembrane signaling molecules and receptors.
LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autosomal dominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms.
Despite its high homology with LGI1 and similar expression pattern, mutations in LGI2 have not been found to be associated with ADTLE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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