Thermo Fisher Scientific TrkA Monoclonal Antibody (6B2)
인간 TrkA 단백질을 검출하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC/IF, ELISA에 적합합니다. 비결합형 액상 형태이며, 4°C 단기 또는 -20°C 장기 보관이 가능합니다. 신경세포 분화 및 MAPK 경로 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6B2 |
| Immunogen | Purified recombinant extracellular fragment of human TrkA (aa33–423) fused with hIgGFc tag expressed in HEK293 cell line |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10978530 |
Product Specific Information
MA5-15509 targets TrkA in indirect ELISA, IF, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant extracellular fragment of human TrkA (aa33–423) fused with hIgGFc tag expressed in HEK293 cells.
MA5-15509 detects TrkA with a predicted molecular weight of approximately 87.4 kDa.
Target Information
NTRK1 (TrkA) belongs to the neurotrophic factor family involved in the development and maintenance of the mammalian nervous system.
TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.
The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes.
Mutations in TrkA are associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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