Thermo Fisher Scientific SMAD9 Polyclonal Antibody
SMAD9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, A549 세포에서 51 kDa 밴드 검출. Protein G 정제, 액상 형태, 4°C 또는 -20°C 보관. 인간 시료에 반응하며 연구용으로만 사용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides corresponding to amino acids 22–36 and 317–331 of human SMAD8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2286514 |
Product Specific Information
PA1-29826 has been successfully used in Western blot applications, where a band of 51 kDa is detected. A549 cells can be used as a positive control for this antibody.
Target Information
SMADs are members of the MAD-related family of molecules. These intracellular proteins are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily.
SMADs are categorized as:
- R-SMADs: SMAD1, 2, 5, 8, and 9
- Co-SMAD: SMAD4
- I-SMADs: SMAD6 and 7
SMAD1, 5, 8, and 9 share high sequence homology, and antibodies are available that recognize common sequences. SMAD8 and SMAD9 are often used interchangeably in literature. Mutations in this gene can lead to pulmonary hypertension, primary 2 (PPH2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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