Thermo Fisher Scientific BACE2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0876)
Recombinant alpaca monoclonal antibody recognizing human BACE2. Suitable for direct ELISA applications. Produced in CHO cells and purified via metal-chelate chromatography. Supplied as liquid in PBS without preservative for research use only.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0876 |
| Immunogen | Recombinant Human BACE2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
BACE2 (Beta Secretase 2) is responsible for the proteolytic processing of the amyloid precursor protein (APP). It cleaves APP between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also known to cleave APP between residues 671 and 672. Accumulation of APP is a hallmark of Alzheimer’s disease and is frequently observed in adult Down syndrome patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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