Thermo Fisher Scientific IL-2 Monoclonal Antibody (5355)
인간 및 비인간 영장류 반응성을 가진 IL-2 단클론 항체. ELISA 및 ICC/IF에 적합하며, 단백질 A/G로 정제된 동결건조 형태. 보존제 무첨가, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 8–25 µg/mL |
| ELISA (Detection) | 0.1–0.4 µg/mL |
| ELISA (Capture) | 2–8 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5355 |
| Immunogen | E. coli-derived recombinant human IL-2 (Ala21–Thr153) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608412 |
Product Specific Information
- In sandwich ELISAs, no cross-reactivity with recombinant human IL-1α, IL-1β, IL-3, IL-4, IL-6, IL-7, IL-8, or recombinant mouse IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine important for the proliferation of activated T cells and differentiation of B cells, NK cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex whose gamma chain is shared by IL-4 and IL-7. Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism. Disruption of the IL-2 gene in mice leads to an ulcerative colitis-like disease, indicating its essential role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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