Thermo Fisher Scientific NR2C1 Monoclonal Antibody (OTI1E9), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments with this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The NR2C1 gene encodes a nuclear hormone receptor containing a conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD), characteristic of the steroid/thyroid hormone receptor superfamily.
This receptor functions as a ligand-inducible transcription factor regulating gene expression by binding to specific DNA sequences within promoters of target genes.
Multiple alternatively spliced transcript variants have been reported, though not all full-length variants are fully characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.