Thermo Fisher Scientific NR2C1 Monoclonal Antibody (OTI1E9), TrueMAB
Human NR2C1 단백질(aa 1-237)에 특이적인 Mouse monoclonal antibody (Clone OTI1E9). Western blot에 적합하며, PBS buffer에 동결건조된 형태로 제공. 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–237 of human NR2C1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments with this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The NR2C1 gene encodes a nuclear hormone receptor containing a conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD), characteristic of the steroid/thyroid hormone receptor superfamily.
This receptor functions as a ligand-inducible transcription factor regulating gene expression by binding to specific DNA sequences within promoters of target genes.
Multiple alternatively spliced transcript variants have been reported, though not all full-length variants are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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