Thermo Fisher Scientific NR2C1 Monoclonal Antibody (OTI4E4), TrueMAB
NR2C1 단백질을 인식하는 Mouse monoclonal 항체로, Western blot에 최적화됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS buffer에 trehalose 포함, -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–237 of human NR2C1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The NR2C1 gene encodes a nuclear hormone receptor with a conserved DNA-binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand-binding domain (LBD), characteristic of the steroid/thyroid hormone receptor superfamily.
This protein functions as a ligand-inducible transcription factor regulating gene expression by binding to specific promoter regions.
Multiple alternatively spliced transcript variants exist, though not all full-length forms have been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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