Thermo Fisher Scientific NR2C1 Monoclonal Antibody (OTI4E4), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The NR2C1 gene encodes a nuclear hormone receptor with a conserved DNA-binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand-binding domain (LBD), characteristic of the steroid/thyroid hormone receptor superfamily.
This protein functions as a ligand-inducible transcription factor regulating gene expression by binding to specific promoter regions.
Multiple alternatively spliced transcript variants exist, though not all full-length forms have been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.