Thermo Fisher Scientific IKZF3 Monoclonal Antibody (OTI5E2), TrueMAB
IKZF3 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체로, 인간 시료에 반응하며 WB 및 IHC(P) 응용에 적합합니다. 고순도 액상 항체로 안정적인 신호 검출을 제공하며, B세포 발달 및 분화 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–301 of human IKZF3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos, and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development.
The gene product acts as a transcription factor regulating B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling.
Regulation of gene expression in B lymphocytes by Aiolos is complex, involving sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers.
At least six alternative transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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