Thermo Fisher Scientific TG Monoclonal Antibody (OTI8A8), TrueMAB
인간 Thyroglobulin을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. 고순도의 Affinity chromatography 정제 제품으로 1 mg/mL 농도의 액상 형태. PBS, BSA, 글리세롤 포함 저장용액에 보존되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–358 of human TG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3.
Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were the first such factor discovered. Anti-hTG is found in all thyroid autoimmune diseases (e.g., Hashimoto thyroiditis, Graves disease), with the highest levels observed in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer, and its detection can be used for follow-up of cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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