
Thermo Fisher Scientific TG Monoclonal Antibody (OTI1F1), TrueMAB
인간 Thyroglobulin(TG)을 표적으로 하는 Mouse IgG1 단일클론 항체. Western Blot 및 IHC(Paraffin) 검증 완료. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TG Monoclonal Antibody (OTI1F1), TrueMAB
Applications and Tested Dilution
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–358 of human TG produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were the first factor discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves disease), with the highest levels observed in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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