Thermo Fisher Scientific KMT2C Polyclonal Antibody
KMT2C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB 및 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 용액 형태로 제공되며, 장기 보관 시 -20°C에서 안정적.
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Applications
- Western Blot (WB): 1:1,000
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human KMT2C (Recombinant protein control fragment, Product #RP-108014) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2664133 |
Product Specific Information
Immunogen sequence:
TPPTMSQPTFP MVPQQLQHQQ HTTVISGHTS PVRMPSLPGW QPNSAPAHLP LNPPRIQPPI AQLPIKTCTP APGTVSNANP Q
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 33%
Target Information
Histone methyltransferase that methylates Lys-4 of histone H3.
H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation.
Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors involved in transcriptional coactivation.
KMT2C/MLL3 may be a catalytic subunit of this complex.
May be involved in leukemogenesis and developmental disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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