Thermo Fisher Scientific CSMD1 Polyclonal Antibody
Rabbit polyclonal antibody against human CSMD1 protein for research use. Recognizes recombinant CSMD1 with high sequence identity to mouse and rat orthologs. Suitable for tumor suppression and immune pathway studies. Liquid form, unconjugated, stored a...
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Thermo Fisher Scientific CSMD1 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CSMD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664471 |
Product Specific Information
Immunogen sequence:
AVGSKVHYFCK PGYRMVGHSN ATCRRNPLGM YQWDSLTPLC QAVSCGIPES PGNGSFTGNE FTLDSKVVYE C
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 88%
Target Information
CSMD1 (CUB and Sushi multiple domains 1) is a protein encoded by the CSMD1 gene in humans. It acts as a potential tumor suppressor, and its deletion may lead to more aggressive head and neck carcinomas.
CSMD1 is part of the complement system, defending against pathogens through the classical or alternative pathway. Primarily located in nerve growth cones, CSMD1 blocks the classical immune pathway and is implicated in tumor suppression, as defects in this gene are associated with squamous cell carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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