Thermo Fisher Scientific CSMD1 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human CSMD1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2664471

Product Specific Information

Immunogen sequence: AVGSKVHYFCK PGYRMVGHSN ATCRRNPLGM YQWDSLTPLC QAVSCGIPES PGNGSFTGNE FTLDSKVVYE C

Highest antigen sequence identity to the following orthologs - mouse 90%, rat 88%.

Target Information

CSMD1 CUB and Sushi multiple domains 1 is a protein that in humans is encoded by the CSMD1gene. It is a potential tumour suppressor, the deletion of which may result in head and neck carcinomas behaving more aggressively. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.