Thermo Fisher Scientific SEC61A1 Polyclonal Antibody
SEC61A1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, Western blot 및 IHC(P) 등에 사용 가능. 인간 반응성, 예측 반응종 포함. 0.5 mg/mL 농도, TBS pH 7.3 버퍼에 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C terminus amino acids KEQSEVGSMGALLF (aa 463–476) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2301613 |
Product Specific Information
- Predicted to react with bovine, canine, and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. It is composed of three subunits—alpha, beta, and gamma—that form a heterotrimer. Multiple heterotrimers associate to form the ER translocon.
Sec61 alpha is a polytopic protein with ten membrane-spanning loops, tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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