Thermo Fisher Scientific alpha-II Spectrin (Cleaved Asp1185) Polyclonal Antibody
인간 alpha-II Spectrin (Cleaved Asp1185)에 특이적인 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 보존제가 없는 액상 형태입니다. 세포골격 단백질 연구 및 세포막 안정화 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino-terminal residues surrounding Asp1185 in human alpha-Spectrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977366 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins stabilizing the plasma membrane and organizing intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin specifically expressed in nonerythrocytic cells. The encoded protein is also involved in DNA repair and cell cycle regulation. Mutations in this gene cause early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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