Thermo Fisher Scientific TRIM5 beta Polyclonal Antibody
TRIM5 beta 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot과 ELISA에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100–200 of human TRIM5 (NP_149083.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914109 |
Product Specific Information
Positive test controls include: HeLa, SGC-7901, Mouse stomach.
The target is usually found in the following locations: Cytoplasm, Nucleus, P-body.
Immunogen sequence:
EKLLLFCQED GKVICWLCER SQEHRGHHTF LTEEVAREYQ VKLQAALEML RQKQQEAEEL EADIREEKAS WKTQIQYDKT NVLADFEQLR DILDWEESNE L
Target Information
The protein encoded by this gene is a member of the tripartite motif family.
The TRIM motif includes three zinc-binding domains (a RING, a B-box type 1, and a B-box type 2) and a coiled-coil region.
The protein forms homo-oligomers via the coiled-coil region and localizes to cytoplasmic bodies.
It functions as an E3 ubiquitin-ligase and ubiquitinates itself to regulate subcellular localization.
It may play a role in retroviral restriction.
Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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