Thermo Fisher Scientific APOBEC3B Recombinant Rabbit Monoclonal Antibody (1M8K2)
Recombinant rabbit monoclonal antibody (clone 1M8K2) specific to human APOBEC3B. Validated for WB and ELISA applications. Produced in HEK293 cells and purified by Protein A. Supplied in PBS with glycerol for stable long-term storage at -20°C.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1M8K2 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 120–220 of human APOBEC3B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.01 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
AARLYYYWER DYRRALCRLS QAGARVTIMD YEEFAYCWEN FVYNEGQQFM PWYKFDENYA FLHRTLKEIL RYLMDPDTFT FNFNNDPLVL RRRQTYLCYE V
Target Information
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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