Thermo Fisher Scientific GREM1 Monoclonal Antibody (2F1)
Thermo Fisher Scientific의 GREM1 Monoclonal Antibody (2F1)은 인간 GREM1 단백질을 표적으로 하는 Mouse IgG2a 형 항체입니다. Western blot과 ELISA에 적합하며, PBS 버퍼에 보존된 액상 형태입니다. 연구용으로만 사용 가능하며 종양 및 신경 발생 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F1 |
| Immunogen | GREM1 (NP_037504, 75 a.a. approximately 184 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ESSQEALHVT ERKYLKRDWC KTQPLKQTIH EEGCNSRTII NRFCYGQCNS FYIPRHIRKE EGSFQSCSFC KPKKFTTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD
Target Information
In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants.
The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13–q15.
DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine, and colon.
It has been suggested that down-regulation of DRM is associated with tumor progression, supporting the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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