Thermo Fisher Scientific GREM1 Monoclonal Antibody (3H4)
Human GREM1 단백질을 인식하는 Mouse IgG2a 단클론 항체로 ELISA에 적합. GST 태그가 포함된 재조합 단백질로 면역화. PBS 버퍼에 보존제 없이 액상 형태로 제공되며, -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
ELISA (ELISA)
- Tested Dilution: 0.03 ng/mL
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H4 |
| Immunogen | GREM1 (NP_037504, 약 75~184 a.a) 부분 재조합 단백질, GST 태그 포함 (GST 태그 MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ESSQEALHVT ERKYLKRDWC KTQPLKQTIH EEGCNSRTII NRFCYGQCNS FYIPRHIRKE EGSFQSCSFC KPKKFTTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD
Target Information
In Xenopus, Gremlin belongs to a novel gene family that acts as BMP antagonists in embryonic explants.
The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13–q15.
DRM-specific mRNA is expressed in various human tissues, including brain, ovary, intestine, and colon.
It has been suggested that down-regulation of DRM is associated with tumor progression, supporting the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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