Thermo Fisher Scientific PLD2 Polyclonal Antibody
PLD2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 1 mg/mL 농도. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PLD2 (Accession O14939), corresponding to amino acid residues P486–P536 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853346 |
Product Specific Information
Antibody detects endogenous levels of total PLD2.
Target Information
PLD2 is a peripheral membrane protein belonging to the phospholipase D family, containing a PH domain, two PLD phosphodiesterase domains, and a PX (phox homology) domain that plays a regulatory role. It catalyzes the hydrolysis of phosphatidylcholine (PC) to produce phosphatidic acid and choline. PLD2 may function in regulated secretion, signal-induced cytoskeletal regulation, endocytosis, transcriptional regulation, and cell cycle control. It is stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and activated by ADP-ribosylation factor-1 (ARF-1). PLD2 interacts with EGFR and PIP5K1A, is localized to plasma membrane caveolae, and is ubiquitously expressed in most tissues.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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