Thermo Fisher Scientific PIGF Polyclonal Antibody
Thermo Fisher Scientific의 PIGF Polyclonal Antibody는 인간 및 마우스 시료에서 PIGF 단백질을 검출하는 토끼 유래 IgG 항체입니다. Western blot에 최적화되어 있으며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PIGF (Accession Q07326), corresponding to amino acid residues W151–V201 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853342 |
Product Specific Information
This antibody detects endogenous levels of total PIGF.
Target Information
Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs are essential for the biosynthesis of the glycosylphosphatidylinositol (GPI) anchor. Some PIG proteins are components of the GPI transamidase complex, recognizing either the GPI attachment signal or the lipid portion of GPI. Others belong to the glycosyltransferase complex, transferring N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI).
PIG-F functions as an auxiliary subunit of ethanolamine phosphate (EtNP) transferases. It associates with PIG-O and is required for its expression and stability. Together, these two PIGs catalyze the transfer of EtNP to the third mannose (Man-3) of GPI. Mutations in the PIG-F gene can block EtNP addition to Man-3, leading to the absence of GPI-anchored proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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