Thermo Fisher Scientific RALA Monoclonal Antibody (4G8B11)
RALA 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, Flow cytometry, ELISA에 적합합니다. Human, Mouse, Non-human primate 반응성이 있으며, Protein G로 정제된 1 mg/mL 액상 형태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA531890
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G8B11 |
| Immunogen | Purified recombinant fragment of human RALA (AA: 71–203) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787513 |
Product Specific Information
MA5-31890 has been tested in indirect ELISA.
Target Information
RALA is a multifunctional GTPase involved in various cellular processes such as gene expression, cell migration, cell proliferation, oncogenic transformation, and membrane trafficking. It functions as a GTP sensor for GTP-dependent exocytosis of dense core vesicles and plays a role in early cytokinesis by tethering the exocyst to the cytokinetic furrow. The RALA–exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. It also regulates LPAR1 signaling by competing with GRK2 for receptor binding and is required for anchorage-independent proliferation of transformed cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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