Thermo Fisher Scientific CD26 (DPP IV/ADA-Binding Protein) Monoclonal Antibody (134-2C2)
CD26(DPP IV/ADA-Binding Protein) 단클론 항체로 인간 시료에 반응합니다. IHC, ICC/IF, Flow Cytometry에 적합하며, Protein L로 정제된 액상 형태입니다. T세포 활성화 및 면역 관련 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 134-2C2 |
| Immunogen | A synthetic peptide from the amino terminal region of CD26 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein L |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD26 (dipeptidyl peptidase IV, DPP IV, adenosine deaminase (ADA) binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family.
It is expressed on lymphocytes and upregulated during T-cell activation, as well as on activated B cells, NK cells, and epithelial cells.
CD26 is involved in T-cell activation, cell adhesion to extracellular matrix proteins (e.g., fibronectin, collagens), and HIV infection.
It is identical to adenosine deaminase complexing protein-2 and the T-cell activation antigen CD26.
Alterations in CD26 peptidase activity are associated with malignant transformation, with enzymatic activity increasing with tumor grade.
Changes in CD26 density have been observed in circulating monocytes and CD4+ T cells in rheumatoid arthritis and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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