Thermo Fisher Scientific NPPB Monoclonal Antibody (OTI3H2), TrueMAB
인간 NPPB 단백질(아미노산 27-102)에 특이적인 Mouse IgG1 단클론 항체. Western blot 및 Luminex 분석에 적합. 액상 형태로 제공되며, PBS/BSA/glycerol 버퍼에 저장. 심혈관 연구 및 BNP 관련 단백질 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Luminex (LUM)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27–102 of human NPPB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein functioning as a cardiac hormone. The protein undergoes two cleavage events—one intracellular and another after secretion into the blood.
Its biological actions include:
- Natriuresis
- Diuresis
- Vasorelaxation
- Inhibition of renin and aldosterone secretion
- Maintenance of cardiovascular homeostasis
High concentrations of this protein in the bloodstream are indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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