Thermo Fisher Scientific UBR4 Polyclonal Antibody
UBR4 단백질을 인식하는 염소 유래 폴리클로날 항체로, 인간 시료에 반응합니다. IHC(P) 등 다양한 응용에 사용 가능하며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. TBS(pH 7.3) 버퍼에 0.5% BSA와 0.02% sodium azide를 포함합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5142505
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-NTTRATSREEKNLQ |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933152 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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