Thermo Fisher Scientific eIF5A Polyclonal Antibody
Human eIF5A 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot과 IHC(P)에서 검증됨. 번역 연장 및 세포 주기 조절 관련 연구에 적합. 0.5 mg/mL 액상 형태, -20°C 보관.
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Thermo Fisher Scientific eIF5A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RPPHRASFLKRLESK) corresponding to the internal amino acids of EIF5A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982352 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
eIF5A is an mRNA-binding protein involved in translation elongation. It plays a role in mRNA turnover, actin dynamics, and cell cycle progression. Also implicated in stress response and maintenance of cell wall integrity. Functions with syntenin (SDCBP) as a regulator of TP53/p53-dependent apoptosis and TNF-alpha-mediated apoptosis. Mediates polyamine effects on neuronal process extension and survival, and may be important for brain development and skeletal muscle stem cell differentiation. Acts as a cellular cofactor for HTLV-1 Rex and HIV-1 Rev proteins, essential for retroviral mRNA export.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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