Thermo Fisher Scientific PEG3 Polyclonal Antibody
PEG3 단백질을 검출하기 위한 Rabbit Polyclonal Antibody로서 WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 형태이며 -20°C에서 보관. 세포 증식 및 종양 억제 연구에 적합.
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- PA599683
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PEG3 (Accession Q9GZU2), corresponding to amino acid residues G1427–G1477. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818616 |
Product Specific Information
Antibody detects endogenous levels of total PEG3.
Target Information
In humans, ZIM2 and PEG3 are treated as distinct genes sharing multiple 5′ exons and a common promoter, both paternally expressed. Alternative splicing connects these shared exons with unique exons specific to each gene.
In other mammals, ZIM2 does not undergo imprinting, and ZIM2 and PEG3 do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family and may play roles in cell proliferation and p53-mediated apoptosis. PEG3 has shown tumor suppressor activity in glioma and ovarian cells. Alternative splicing produces multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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